COST B11 - Workplan 2001

 

Working group 1

Working group 2

Working group 3

Draft Agenda

Working Group 3: Texture Formation

(Co-ordinator: Lothar Schad)

Context

Since its introduction into medical imaging in the mid eighties, magnetic resonance imaging (MRI) has become a powerful in-vivo diagnostic tool. The objective of this Working Group is to progress developments in quantitative MRI, in particular texture analysis, to maximize the diagnostic information. A fundamental part of the work will be a careful study of the optimal MR data collection strategies for the texture analysis task. This is critical, since different centers may vary their measuring sequences and acquisition protocols for the clinical task and be reluctant to vary these for the texture investigation. Different measuring techniques, such as spin echo, gradient echo, echo planar etc., and different measuring parameters produce a totally different pattern in the texture parameters. A careful investigation of the dependency of all these variables studied in texture phantoms is the basic of the understanding on how MR image texture is formed in tissue structures.

Goals

To design and test reliable and accurate test objects that allow the detailed assessment of texture analysis methods in MRI. The issue of these test objects is their ability to simulate tissue-like textures with tissue-like NMR relaxation properties. Long term stability is also vital, as is uniformity of the overall texture. Another aspect is to test the developed texture test objects under a range of different MRI measuring sequences and imaging conditions on different scanners throughout the consortium to determine their stability and utility.

Work Program

Texture Test Objects:

Texture Modeling: MRI Pulse Sequences: Working Methods

Different test objects will be manufactured from existing reticulated foam materials. Relaxation characteristics will be evaluated by T1 and T2 relaxation studies to generate tissue equivalent carrier material for the test objects. In the next step, different containers will be filled with both gel and foam of different pore sizes and measured at different clinical MR scanners. For Siemens scanners, specific pulse sequences will be developed using the software tool PARGEN. These pulse sequences allow to study the influence of signal-to-noise ratio and sequence parameters on texture parameters under controlled conditions.

Organization and Management

The Working Group will be managed from the German Cancer Research Center (DKFZ) in Heidelberg, Germany. External experts and cooperating groups will be recruited from scientific groups with a background of texture formation (US, MRI, CT) or MR pulse sequence development. Candidates are (preliminary):

COST members:

External Experts: Publications Annual Plan and Distribution of Tasks 2000

01/2000 – 03/2000:

04/2000 – 06/2000: 07/2000 – 12/2000: Annual Plan and Distribution of Tasks 2001

01/2001 – 03/2001:

04/2001 – 06/2001: 07/2001 – 12/2001:

Working group 4

 

 
 
 
 
 


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